PH AND ROS SEQUENTIALLY RESPONSIVE PODOPHYLLOTOXIN PRODRUG MICELLES WITH SURFACE CHARGE-SWITCHABLE AND SELF-AMPLIFICATION DRUG RELEASE FOR COMBATING MULTIDRUG RESISTANCE CANCER

Multidrug resistance (MDR) is one of the main reasons for tumor chemotherapy failure.Podophyllotoxin (PPT) has been reported that can suppress MDR cancer cell growth; however, effective delivery of PPT to MDR cancer cells is challenged by cascaded bio-barriers.To effectively deliver PPT to MDR cancer cells, a PPT polymeric prodrug micelle (PCDMA) w

This article aims to commemorate an extraordinary event called Industrial Disaster.This disaster occurred a long time, where the source bursts can not be stopped until now.Casualties are quite a lot, there is even a village wiped off the map, because the entire surface of the devastated hit by the mud.Settlement of sosial 5 Piece Queen Bookcase Bed

Salmonella is a zoonotic foodborne bacterial pathogen that can seriously harm health.Persistence of Salmonella and antibiotic resistance genes (ARGs) in different types of soil under flooding and natural conditions are rare explored.This study investigated the dynamic changes of the Salmonella, ARGs and bacterial communities in three types of soils

Abstract Aedes aegypti (Linnaeus) is an invasive mosquito species and notable vector of several pathogens in the USA.Their cryptic and anthropophilic nature puts this species in close association with humans, where they can also be Circle S Barrel Saddle a nuisance.Mosquito control programs are the front line of defense for protecting the community